eBulletin Newsletter
NCCN Flash Updates: NCCN Guidelines Updated for Hematopoietic Cell Transplantation
NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) and the NCCN Drugs & Biologics Compendium (NCCN Compendium®) for Hematopoietic Cell Transplantation. These NCCN Guidelines® are currently available as Version 2.2023.
Link directly to the Updates section of the NCCN Guidelines: Hematopoietic Cell Transplantation
HCT-4
- Hematopoietic Cell Mobilization
- Treatment
- Stem cell mobilization for autologous donors
- Regimen added: G-CSF + motixafortide
- Footnote added: Motixafortide is indicated in combination with filgrastim (G-CSF) to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with multiple myeloma. Crees ZD, et al. Nat Med 2023;29:869-879. (Also for HCT-4A)
- Stem cell mobilization for autologous donors
- Treatment
HCT-4A
- Hematopoietic Cell Mobilization Regimens
- Autologous Donors
- Regimen and dosing added:
- Filgrastim + Motixafortide
- Filgrastim: 10 mcg/kg SC daily x 4 days prior to first dose of motixafortide
- Motixafortide: 1.25 mg/kg actual body weight SC 10-14 hours prior to initiation of apheresis
- Filgrastim + Motixafortide
- Regimen and dosing added:
- Autologous Donors
For the complete updated versions of the NCCN Guidelines, NCCN Guidelines with NCCN Evidence Blocks™, the NCCN Drugs & Biologics Compendium (NCCN Compendium®), the NCCN Biomarkers Compendium®, the NCCN Chemotherapy Order Templates (NCCN Templates®), the NCCN Radiation Therapy Compendium™, and the NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™), please visit NCCN.org.
To view the NCCN Guidelines for Patients®, please visit NCCN.org/patientguidelines.
Free NCCN Guidelines apps for iPhone, iPad, and Android devices are now available! Visit NCCN.org/apps.
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